Although nicotinamide riboside (NR) is known as a highly efficient precursor of NAD+, its cousin, nicotinamide mononucleotide (NMN), is making significant waves as a new ingredient in With-N Cell Activation Renewal from RenovoVita.

NAD+ (nicotinamide adenine dinucleotide) is a critical coenzyme found in every cell of the body. As we age, our level of NAD+ begins to naturally decline. This makes it essential to supplement if we are to maintain great health as we begin to age.

Supplementing with precursors that can create NAD+ in the body can boost energy levels, lead to less oxidative stress, increase focus and concentration, improve mood, reduce anxiety levels, and help slow down and even reverse the aging process visibly.

There are two different ways that NAD+ can be supplemented. You can choose to take NMN (Nicotinamide mononucleotide) or NR (Nicotinamide riboside).

Although both of these precursors are structurally similar, one significant difference is that the phosphate group on NMN is molecularly larger than NR. Researchers previously believed that before it could enter cells, NMN had to transform into NR. However, new research has shown that certain tissues can help facilitate the conversion of NMN directly to NAD+ by activating a receptor known as Slc12a8.

The findings of these studies suggest that various tissues may prefer NMN over NR.

Once inside a cell, NMN is one step closer to becoming an NAD+ precursor than NR. This is because the latter has to be converted to the former before it can be converted to this chemical. On the other hand, the immediate precursor of NAD+, which is also known as NMN, only requires one step to convert to this chemical.

It is, for this reason, we chose to formulate With-N Cell Activation Renewal using pharmaceutical-grade NMN.

Raising the level of NAD+ is vital to cellular metabolism. It is involved in hundreds of metabolic processes, such as maintaining DNA health and activating sirtuins.

Getting the necessary NAD+ from our diet is very important for our bodies but while trace amounts of both NR and NMN can be found in foods it’s not possible to eat enough to affect NAD+ levels. As a result, supplementation can help mitigate the eventual decline.

If you are over the age of 25 (this is the age where NAD+ first begins to decline) you can benefit from supplementing with an NMN to NAD+ boosting supplement. To learn more or shop, visit www.RenovoVita.com/With-N.